When you guys mention NAS, what kinds of stumbling blocks am I going to find in setting Crashplan up on Windows to back up specific folders, including the boot partition, to my NAS sitting on the same subnet?

This is really the only thing I need the software for, because honestly, all other backup software I've tried or read about just sounds like complete garbage. There just isn't any decent software available for Windows for this purpose. Nothing as nice as Time Machine in Mac OS at all.

My other option was just to set up a few scheduled backups via the ReadyNAS UI using rsync.