Crashplan is definitely the new darling, easily beating out Carbonite.

Crashplan offers (for a not-insignificant amount of money) to send you a drive to back up to and mail back to them. I don't know if they do multiple hard drives, and if not, that still means only 2TB at a likely maximum, if not less.

When my Mozy plan runs out I'll be switching to Crashplan. I'm already recommending it to clients.