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Does anyone know how to (really) disable *all* pop-up messages from the tray area? I don't need to be reminded that some files haven't been used in a long time, to turn on auto update, etc... All the other shit Windows is constantly throwing in your face.

I don't know if there is a way of doing it globally.

Control Panel -> Security Center -> Change the way Security Center alerts me -> *uncheck boxes* will stop Firewall/Virus/Update nagging.

Control Panel -> Display -> Desktop -> Customize Desktop -> *uncheck Run Cleanup Wizard* will stop that annoying rubbish that I haven't actually seen anyone ever use.

Then there is that "Welcome to Windows!" balloon which pops up when you login to a freshly installed machine. I think if you actually click on it instead of swearing at it and then click the cancel button in the resulting window it goes away for good.
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Hussein