I don't think any of the holes will line up with any of the screws on the empeg drive tray and also allow the cable to reach. Though admittedly I haven't yet opened an empeg to check.

Sure I could stick it down, but they I'm likely to have to deal with whatever I stick it down with failing in time. I naively assumed this would have holes to match a real drive

I have certainly used some laptops where this CF holder definitely would not be usable due to the lack of screw alignment.