If any of your folders or file names contain spaces, then you need to convert to short file names, or perhaps surround them with quotes.

For instance, if your ActivePython is installed to "C:\program files\python\", and your parse_mapsonus.py is in "c:\program files\map parser\", and the HTM file was in "C:\My Documents\", then the line would be:

C:\progra~1\Python\python.exe C:\progra~1\mappar~1\parse_mapsonus.py C:\mydocu~1\myroute.htm

The other trick is you have to make sure the spaces are in the correct places.